One CRO

For Your Preclinical R&D Needs

We want to simplify your CRO experience.

You can now work with just one CRO for the majority of your drug development and consulting needs.

Consulting

Working with us starts with a plan

scientific

  • Drug development road map
  • Experimental path to value inflection
  • Therapeutic indication selection
  • Mechanism of action 
  • Lead candidate selection
  • Protocol development

Scientific

strategic

  • Drug assets positioning
  • Portfolio and platform strategy
  • Therapeutic area prioritization
  • Competitive landscape
  • Pitch deck assistance
  • Investor and pharma partner selection and introductions

Strategic

Contract Research

We offer a wide range of Preclinical services

BIONALAYTICS

  • High throughput sequencing
  • Single cell sequencing
  • Single crystal structural analysis
  • Nuclear magnetic resonance
  • Liquid chromatography-mass spec
  • Gas chromatography-mass spec
  • High-performance liquid chromatography
  • Inductively coupled plasma optical emission spectrometry
  • MALDI Matrix chromatography

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bioanalytics

Imaging

  • Live cell imaging
  • Multispectral fluorescence animal imaging
  • Total internal reflection fluorescence
  • Confocal microscopy
  • Cyclotron/ radiochemistry
  • Magnetic resonance imaging
  • Positive emission tomography
  • Computerized tomography
  • Conventional transmission and scanning electron microscopy
  • Cryo-high resolution SEM
  • Cryo-tomography
  • Field emission transmission electron microscopy

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imaging

cell & gene therapies

  • Gene editing/ CRISPR
  • Gene targeting
  • Transgenic animals
  • Embryonic stem cells
  • Induced pluripotent stem cells
  • Cell isolation and characterization
  • Cell therapy optimization
  • Transduction and transfection optimization

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cell & gene therapies

BIOmarkers

  • Flow cytometry
  • Genomics and epigenetics
  • Proteomics
  • Lipodomics and secretomics
  • Glycomics
  • Metabolomics
  • V-Plex and U-Plex immunoassays
  • SNP microarrays
  • lmmunohistochemistry

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biomarkers

antibodies, biologics

  • Monoclonal and polyclonal antibodies production
  • Analytical testing and characterization
  • Peptide production and purification
  • Phage, bacterial and yeast displays
  • Cell line development
  • Culture optimization
  • Fermentation: bacterial yeast, mycelial and plant cell culture 

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antibodies, biologics

animal models

  • Select oncology animal models
  • Gnotobiotic animal models
  • Transgenic animal models
  • HIV/SIV non-human primate (NHP) model
  • RSV and flu NHP models
  • Cystic fibrosis rodent models
  • Malaria NHP model
  • • NHP immunity models
  • Type I and 2 diabetes NHP model
  • Metabolic syndrome NHP model
  • Obesity NHP model
  • Cardio-pulmonary rodent and NHP models
  • Fat biopsy (NHP)
  • PK/Tox studies (NHP)
  • Right heart catheterization and left heart analysis (NHP) 
  • Kidney failure small animal models
  • Liver ischemia-reperfusion small animal models
  • Veterinary medicine, small and large animal models

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animal models

therapeutic areas

immunology

  • Cytokine, chemokine profiling
  • Immune cell phenotyping
  • Biomarkers
  • lmmunoassays
  • Human TCR repertoire sequencing
  • lmmunohistochemistry and histopathology
  • Transgenic animal models
  • CRISPR gene editing
  • Antibody characterization and development
  • NHP immunity models
  • Microbiome
  • Vaccines

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immunology

  • Cytokine, chemokine profiling
  • Immune cell phenotyping
  • Biomarkers
  • lmmunoassays
  • Human TCR repertoire sequencing
  • lmmunohistochemistry and histopathology
  • Transgenic animal models
  • CRISPR gene editing
  • Antibody characterization and development
  • NHP immunity models
  • Microbiome
  • Vaccines

immunology

Oncology

  • Cell lines and tumor tissue repository
  • Syngeneic, transgenic, xenograft and PDX mouse models
  • Efficacy studies as single agent or in combination
  • Non-GLP toxicology and PK/PD studies (mice, rats, dogs, NHP)
  • In vivo optical bioluminescent and fluorescent imaging
  • Surgical cranial window placement
  • Complete necropsy and tissue collection
  • Histopathology and biochemical analysis

 

 

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Oncology

  • Cell lines and tumor tissue repository
  • Syngeneic, transgenic, xenograft and PDX mouse models
  • Efficacy studies as single agent or in combination
  • Non-GLP toxicology and PK/PD studies (mice, rats, dogs, NHP)
  • In vivo optical bioluminescent and fluorescent imaging
  • Surgical cranial window placement
  • Complete necropsy and tissue collection
  • Histopathology and biochemical analysis

 

 

Oncology

infectious diseases

  • BSL3 facilities
  • Pathogen profiling
  • Microbiome
  • Gnotobiotic animal models
  • HIV/SIV non-human primate (NHP) model
  • RSV and flu NHP models
  • Malaria NHP model
  • Cystic fibrosis rodent models
  • RNA viruses models and methods
  • Veterinary medicine, small and large animal models

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infectious diseases

  • BSL3 facilities
  • Pathogen profiling
  • Microbiome
  • Gnotobiotic animal models
  • HIV/SIV non-human primate (NHP) model
  • RSV and flu NHP models
  • Malaria NHP model
  • Cystic fibrosis rodent models
  • RNA viruses models and methods
  • Veterinary medicine, small and large animal models

infectious diseases

Metabolic & CV Diseases

  • Metabolomics
  • Glycomics
  • Lipidomics
  • Proteomics
  • Type I and 2 diabetes NHP model
  • Metabolic syndrome NHP model
  • Obesity NHP model
  • Cardio-pulmonary rodent and NHP models
  • Kidney failure small animal models
  • Liver ischemia-reperfusion small animal models

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Metabolic & CV Diseases

  • Metabolomics
  • Glycomics
  • Lipidomics
  • Proteomics
  • Type I and 2 diabetes NHP model
  • Metabolic syndrome NHP model
  • Obesity NHP model
  • Cardio-pulmonary rodent and NHP models
  • Kidney failure small animal models
  • Liver ischemia-reperfusion small animal models

metabolic diseases

neurology

  • Neurosurgical services
  • lntraparenchymal and intrathecal delivery
  • Viral vector drug delivery
  • Brain and spinal cord harvesting
  • In vitro and in vivo automated intracellular and extracellular recordings
  • Cell culture and brain histology
  • Rodent behavioral models: pain, depression and anxiety

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neurology

  • Neurosurgical services
  • lntraparenchymal and intrathecal delivery
  • Viral vector drug delivery
  • Brain and spinal cord harvesting
  • In vitro and in vivo automated intracellular and extracellular recordings
  • Cell culture and brain histology
  • Rodent behavioral models: pain, depression and anxiety

Neurosciences

Next Steps

We would love to hear your story.

support@radyusresearch.com

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